Two independent algorithms – Consensus Genotyping and Statistical Genotyping
Consensus Genotyping: – De novo assembly: optimal for fully phased consensus sequences – Reference alignment: added analytical confidence, novel allele detection and null allele resolution
Analyze data against any version of the IMGT/HLA Database
DRB, DQ Linkage Disequlibrium checks
Quality
24 Quality Control metrics for confident assignment and detailed troubleshooting
Traffic Light System for easy interpretation of genotyping results
Whole Gene Consensus sequences for unambiguous allele assignment
Complete Novel and Null allele detection
Automation and Integration
Fully automated analysis after Illumina sequencing run
Export genotyping results – HML, PDF, JSON, XLS
Integration with LIMS, such as Histotrac and mTilda
Simple assignment and multi-layer approval workflows
Simple and customizable allele assignment for ease of use
Flexibility & Scalability
Platform independent (available for Windows, Linux and macOS)
Desktop and Client-Server versions
Customizable analysis and visualization
Note: HLA Twin is sold as part of Holotype HLA and is not available for download from our website. Please contact support@omixon.com for more information.