FluidLab R-300 Cell Counter with Integrated Spectrometer

Fluidlab R-300

Devices, Carrier and Software

Anvajo is a developer and manufacturer of point-of-care solutions for laboratory diagnostics, providing accurate devices, multifunctional sample carrier systems and robust software suites.

Anvajo’s innovative devices combine a miniaturized spectrometer with a digital microscope, catering for point-of-need diagnostics in various industries. Target samples include amongst others, blood, urine, sperm and water. Test pre-analytics are supported by a system of dedicated sample carriers, which process and deliver the fluid to be analysed.

Central areas of application include human and veterinary medicine, environmental analysis and research. anvajo’s robust software suites have been especially designed for scientists and researchers, allowing direct access to raw data and enabling clinical and scientific advance.

The fluidlab R-300

The fluidlab R-300 is the smallest, most comfortable laboratory instrument on the market. It combines a full-fledged spectrometer with an automatic cell counter. Its intuitive handling and precise measurements make the fluidlab R-300 the laboratory instrument of the future. With standard cuvettes as well as with glass sample carriers from anvajo a variety of analyses such as absorbance, automatic cell counting and staining-free viability measurements can be performed.

Measure viability without staining: Cytotoxic effects and measurement errors are eliminated by staining-free determination of the viability. Standardized cell count and viability measurements also lead to improved predictability and quality of your experiments.

The fluildab R-300 is the smallest spectrometer in the range from 375 to 700 nm with a spectral resolution of less than 2 nm. The fluildab R-300 is linear in the range of 0 – 2.5 absorbance units with a photometric accuracy of 0.01.

The results are available within 1 minute. A large “field-of-view” (5.3 mm²) and automated measurement of the cell count reduce human error and increase statistical certainty.

The fluidlab R-300 has a wizard for automatic calibration curves. By saving the curves, an automatic calculation and sample quantification is possible.

The fluidlab R-300 in comparison

An NGS protocol for HLA typing that enables you to reduce your processing turnaround and hands-on time significantly in a single working day.

Accuracy and reliability of the fluidlab R-300

Cell Count Linearity of the R-300 against manual cell counting using a hemocytometer

Linearity of Trypan Blue Serial Dilutions

PBMC’s viability monitored as function of DMSO concentration

Modular Adapter System

Anvajo provides a variety of sample carrier systems for different types of applications within diagnostics. The fluidlab device adapts to microfluidic, mesofluidic and macrofluidic sample carriers using specifically designed slot adapters that enable smooth intake from slides to cuvettes. Scientists and researchers around the world are encouraged to co-develop custom sample carriers for their specific assays and applications. Please contact our responsible experts for further details on the usage and development of anvajos modular sample carrier system.

Our sample carrier portfolio at a glance

Acella

acella is a proprietary sample carrier format that uses a glass substrate. Its low sample chamber heights make the acella a perfect fit for microscopic applications such as cell counting or particle classification. Beyond that, this carrier is the optimal choice for spectrophotometric analyses of fluids with high optical densities such as whole blood.

Models:

  • acella 50: sample chamber height 50 µm, glass substrate
  • acella 20: sample chamber height 20 µm, glass substrate
  • acella 100: sample chamber height 100 µm, glass substrate

Areas of application:

  • Microscopic analysis of particles in fluids
  • Spectrophotometric analysis of fluids with high optical densities

Examples of applications:

  • General cell counting and basic classification (yeast, HeLa, algea, stem cells, leukocytes)
  • General particle counting and basic classification
  • Haemoglobin in whole blood
  • Haematocrit in whole blood
  • Fluid condition monitoring, fluid cleanliness management

User groups:

  • Yeast: Scientists working in cell culture, assay development, breweries, craft beer brewer
  • HeLa: Scientists working in cell culture, oncology
  • Algae: biofuel production, algae food production
  • Stem cells: oncology, regenerative medicine
  • Leukocytes: GPs, Pediatric MDs

 

Cuvette

The cuvette format is one of the most popular sample carrier standards for fluid testing in laboratories worldwide. It is the sample carrier of choice for simple spectrophotometric measurements of fluids with low optical densities. Anvajo supports various cuvette formats.

Professional software for researchers and scientists

The anvajo imaging suite* is a desktop application explicitly created for scientists and researchers. It provides direct access to the raw data of any test result providing instant access to clinical and scientific findings. This software suite enables and encourages users to develop their own test methods based on the anvajo technology platform.

The anvajo imaging suite in a nutshell

  • A modern and multi-functional desktop client based on the fluidlab platform that is suitable for all devices
  • Incorporates advanced microscopic and spectrophotometric analysis features (e.g. configuration of sensor settings, time series testing, …)
  • Provides users with access to the fluidlabs raw data which can be exported to other tools (e.g. MATLAB, Excel, …)
  • Provides additional fluidlab configuration options
  • Enables scientists to test many different types of fluids on the fluidlab device
  • Allows users to create their own test recipes for future distribution in specific markets

 

Impressions of the anvajo imaging suite

*Software not yet available